TTR Antikörper (full length)
Kurzübersicht für TTR Antikörper (full length) (ABIN7879206)
Target
Alle TTR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- Transthyretin Antibody / TTR / Prealbumin
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Recombinant human full-length protein was used as the immunogen for the Transthyretin antibody.
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Isotyp
- IgG2c, kappa
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Applikationshinweise
- Optimal dilution of the Transthyretin antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Transthyretin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TTR (Transthyretin (TTR))
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Andere Bezeichnung
- Transthyretin
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Hintergrund
- Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).
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UniProt
- P02766
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Pathways
- Hormone Transport
Target
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