Rekombinanter Transgelin Antikörper (full length)

Produktnummer ABIN7879182

Der Maus Monoklonal anti-Transgelin Antikörper wird verwendet zum Nachweis von Transgelin in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter Transgelin Antikörper (full length) (ABIN7879182)

Target: Transgelin (TAGLN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transgelin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RTAGLN-8975

Produktdetails anti-Transgelin Antikörper

Bindungsspezifität: full length

Verwendungszweck: Recombinant Transgelin Antibody / SM22 alpha

Sequenz: TAGLN

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human Transgelin (TAGLN) protein was used as the immunogen for the recombinant Transgelin antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Transgelin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Transgelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Transgelin

Target: Transgelin (TAGLN)

Andere Bezeichnung: Transgelin

Hintergrund: This mAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.

UniProt: Q01995