SRF Antikörper (full length)

Produktnummer ABIN7879006

Der Maus Monoklonal anti-SRF Antikörper (Klon PCRP-SRF-1F1) (ABIN7879006) detektiert spezifisch SRF in WB, ELISA, IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SRF Antikörper (full length) (ABIN7879006)

Target: SRF (Serum Response Factor (SRF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-SRF-1F1

Produktdetails anti-SRF Antikörper

Bindungsspezifität: full length

Verwendungszweck: SRF Antibody / Serum Response Factor (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human SRF protein was used as the immunogen for the SRF antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SRF antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SRF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SRF

Target: SRF (Serum Response Factor (SRF))

Andere Bezeichnung: SRF

Hintergrund: Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino-terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.

UniProt: P11831