SRF Antikörper (full length)

Produktnummer ABIN7879005

Der Maus Monoklonal anti-SRF Antikörper wird verwendet zum Nachweis von SRF in Proben von Human. Er wurde validiert für WB, ELISA, IF, IHC (p) und FACS.

Kurzübersicht für SRF Antikörper (full length) (ABIN7879005)

Target: SRF (Serum Response Factor (SRF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: PCRP-SRF-1F7

Produktdetails anti-SRF Antikörper

Bindungsspezifität: full length

Verwendungszweck: Serum Response Factor Antibody / SRF

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the Serum Response Factor antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Serum Response Factor antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Serum Response Factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SRF

Target: SRF (Serum Response Factor (SRF))

Andere Bezeichnung: Serum Response Factor

Hintergrund: Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino-terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.

UniProt: P11831