SCXA Antikörper (full length)

Produktnummer ABIN7878977

Dieser Maus Monoklonal Antikörper detektiert spezifisch SCXA in FACS und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SCXA Antikörper (full length) (ABIN7878977)

Target: SCXA (Scleraxis (SCXA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SCXA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: PCRP-SCXA-2D11

Produktdetails anti-SCXA Antikörper

Bindungsspezifität: full length

Verwendungszweck: SCXA Antibody / Scleraxis

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human Basic helix-loop-helix transcription factor scleraxis protein was used as the immunogen for the SCXA antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SCXA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SCXA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SCXA

Target: SCXA (Scleraxis (SCXA))

Andere Bezeichnung: SCXA

Hintergrund: Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains one bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

UniProt: Q7RTU7