PBX2 Antikörper (full length)

Produktnummer ABIN7878837

Der Maus Monoklonal anti-PBX2 Antikörper wird verwendet zum Nachweis von PBX2 in Proben von Human. Er wurde validiert für ELISA, IF und FACS.

Kurzübersicht für PBX2 Antikörper (full length) (ABIN7878837)

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PBX2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-PBX2-1C4

Produktdetails anti-PBX2 Antikörper

Bindungsspezifität: full length

Verwendungszweck: PBX2 Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human PBX2 protein was used as the immunogen for the PBX2 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PBX2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PBX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PBX2

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Andere Bezeichnung: PBX2

Hintergrund: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development