PCGF3 Antikörper (full length)

Produktnummer ABIN7878825

Der Maus Monoklonal anti-PCGF3 Antikörper wird verwendet zum Nachweis von PCGF3 in Proben von Human. Er wurde validiert für IF, IHC (p) und FACS.

Kurzübersicht für PCGF3 Antikörper (full length) (ABIN7878825)

Target: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PCGF3 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-PCGF3-1D5

Produktdetails anti-PCGF3 Antikörper

Bindungsspezifität: full length

Verwendungszweck: PCGF3 Antibody / Polycomb group RING finger protein 3 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the PCGF3 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PCGF3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PCGF3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PCGF3

Target: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Andere Bezeichnung: PCGF3

Hintergrund: Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.

UniProt: Q3KNV8

Pathways: Chromatin Binding