PDLIM1 Antikörper (full length)

Produktnummer ABIN7878783

Der Maus Monoklonal anti-PDLIM1 Antikörper wird verwendet zum Nachweis von PDLIM1 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für PDLIM1 Antikörper (full length) (ABIN7878783)

Target: PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDLIM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: CPTC-PDLIM1-1

Produktdetails anti-PDLIM1 Antikörper

Bindungsspezifität: full length

Verwendungszweck: PDLIM1 Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human full-length PDLIM1 protein was used as the immunogen for this PDLIM1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PDLIM1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the PDLIM1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu PDLIM1

Target: PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

Andere Bezeichnung: PDLIM1

Hintergrund: CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species.

UniProt: O00151