NME2 Antikörper (full length)
Kurzübersicht für NME2 Antikörper (full length) (ABIN7878747)
Target
Alle NME2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- NDPK-B Antibody / Nucleoside diphosphate kinase B / NME2
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Aufreinigung
- Protein G affinity
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Immunogen
- A recombinant full-length human Nucleoside diphosphate kinase B protein was used as the immunogen for the NDPK-B antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the NDPK-B antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the NDPK-B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NME2 (Nucleoside diphosphate kinase B (NME2))
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Andere Bezeichnung
- NDPK-B
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Hintergrund
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
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UniProt
- P22392
Target
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