NEUROD2 Antikörper (full length)
Kurzübersicht für NEUROD2 Antikörper (full length) (ABIN7878708)
Target
Alle NEUROD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- NEUROD2 Antibody
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant full-length human NEUROD2 protein was used as the immunogen for the NEUROD2 antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the NEUROD2 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the NEUROD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))
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Andere Bezeichnung
- NEUROD2
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Hintergrund
- Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
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UniProt
- Q15784
Target
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