MEF2B Antikörper (full length)

Produktnummer ABIN7878685

Der Maus Monoklonal anti-MEF2B Antikörper (Klon PCRP-MEF2B-2F9) (ABIN7878685) detektiert spezifisch MEF2B in WB, IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MEF2B Antikörper (full length) (ABIN7878685)

Target: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MEF2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-MEF2B-2F9

Produktdetails anti-MEF2B Antikörper

Bindungsspezifität: full length

Verwendungszweck: MEF2B Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human MEF2B protein was used as the immunogen for the MEF2B antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MEF2B antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MEF2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MEF2B

Target: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Andere Bezeichnung: MEF2B

Hintergrund: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

UniProt: Q02080