Der Maus Monoklonal anti-MED22 Antikörper (Klon PCRP-MED22-2A7) (ABIN7878592) detektiert spezifisch MED22 in ELISA, IF und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
MED22
Reaktivität: Human
ELISA, WB
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Optimal dilution of the MED22 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the MED22 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
MED22
(Mediator Complex Subunit 22 (MED22))
Andere Bezeichnung
MED22
Hintergrund
Med22 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. Functioning as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, the mediator complex is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Med22 (mediator complex subunit 22), also known as SURF5 (surfeit locus protein 5), is a ubiquitously expressed 200 amino acid nuclear protein that is one of several components of the mediator complex. There are two isoforms of Med22 that are produced as a result of alternative splicing events.