Rekombinanter KRT15 Antikörper (full length)

Produktnummer ABIN7878483

Der Kaninchen Monoklonal anti-KRT15 Antikörper wird verwendet zum Nachweis von KRT15 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter KRT15 Antikörper (full length) (ABIN7878483)

Target: KRT15 (Keratin 15 (KRT15))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KRT15 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: KRT15-8312R

Produktdetails anti-KRT15 Antikörper

Bindungsspezifität: full length

Verwendungszweck: Cytokeratin 15 Antibody / KRT15

Aufreinigung: Protein A affinity

Immunogen: Recombinant human full-length KRT15 protein was used as the immunogen for the Cytokeratin 15 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cytokeratin 15 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Cytokeratin 15 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu KRT15

Target: KRT15 (Keratin 15 (KRT15))

Andere Bezeichnung: Cytokeratin 15

Hintergrund: Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. KRT15 is downregulated in activated keratinocytes. It is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

UniProt: P19012