Cytokeratin 13 Antikörper (full length)
Kurzübersicht für Cytokeratin 13 Antikörper (full length) (ABIN7878479)
Target
Alle Cytokeratin 13 (KRT13) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- Cytokeratin 13 Antibody / KRT13
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A recombinant full-length human KRT13 protein was used as the immunogen for this Cytokeratin 13 antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the Cytokeratin 13 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Cytokeratin 13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
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Andere Bezeichnung
- Cytokeratin 13
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Hintergrund
- Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.
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UniProt
- P13646
Target
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