Der Maus Monoklonal anti-Cytokeratin 13 Antikörper (Klon KRT13-2659) (ABIN7878478) detektiert spezifisch Cytokeratin 13 in IF, IHC (p) und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
KRT13
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
4F5
unconjugated
Applikationshinweise
Optimal dilution of the Cytokeratin 13 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the Cytokeratin 13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
Cytokeratin 13 (KRT13)
(Keratin 13 (KRT13))
Andere Bezeichnung
Cytokeratin 13
Hintergrund
Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.