GTF2IRD2 Antikörper (full length)
Kurzübersicht für GTF2IRD2 Antikörper (full length) (ABIN7878330)
Target
Alle GTF2IRD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- GTF2IRD2 alpha Antibody / GTF2IRD2 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant full-length human General transcription factor II-I repeat domain-containing protein 2A protein was used as the immunogen for the GTF2IRD2 alpha antibody.
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal dilution of the GTF2IRD2 alpha antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the GTF2IRD2 alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
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Andere Bezeichnung
- GTF2IRD2 alpha
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Hintergrund
- The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (also called GTF2IRD2 alpha and GTF2IRD2A) and GTF2IRD2B. Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.
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UniProt
- Q86UP8
Target
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