GTF2H2C Antikörper (full length)

Produktnummer ABIN7878282

Der Maus Monoklonal anti-GTF2H2C Antikörper wird verwendet zum Nachweis von GTF2H2C in Proben von Human. Er wurde validiert für WB, IF, IHC (p) und FACS.

Kurzübersicht für GTF2H2C Antikörper (full length) (ABIN7878282)

Target: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GTF2H2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-GTF2H2C-2C9

Produktdetails anti-GTF2H2C Antikörper

Bindungsspezifität: full length

Verwendungszweck: GTF2H2C Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human GTF2H2C protein was used as the immunogen for the GTF2H2C antibody.

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GTF2H2C antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot the GTF2H2C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu GTF2H2C

Target: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Andere Bezeichnung: GTF2H2C

Hintergrund: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

UniProt: Q6P1K8