Gastrin Antikörper (full length)

Produktnummer ABIN7878263

Dieser Maus Monoklonal Antikörper detektiert spezifisch Gastrin in ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Gastrin Antikörper (full length) (ABIN7878263)

Target: Gastrin (GAST)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Gastrin Antikörper ist unkonjugiert

Applikation: ELISA

Klon: GAST-2635

Produktdetails anti-Gastrin Antikörper

Bindungsspezifität: full length

Verwendungszweck: Gastrin Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant full-length human GAST protein was used as the immunogen for this Gastrin antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Gastrin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Gastrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Gastrin

Target: Gastrin (GAST)

Andere Bezeichnung: Gastrin

Hintergrund: Gastrin, is a hormone that normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets. Its primary function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. It also responsible for stimulating smooth muscle contraction and increasing blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger-Ellison syndrome. Gastrin-Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones and also acts as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems.

UniProt: P01350