EIF2C3 Antikörper (full length)
Kurzübersicht für EIF2C3 Antikörper (full length) (ABIN7878207)
Target
Alle EIF2C3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- AGO3 Antibody / Argonaute-3 / eIF2C3 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant full-length human AGO3 protein was used as the immunogen for the AGO3 antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the AGO3 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the AGO3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
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Andere Bezeichnung
- AGO3
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Hintergrund
- This antigen is involved in binding and translation repression of short RNAs. This antigen is also known as Argonaute RISC catalytic component 3. Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5-flanking sequences to the region of guide-target complementarity.
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UniProt
- Q9H9G7
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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