Elastin Antikörper (full length)

Produktnummer ABIN7878163

Der Maus Monoklonal anti-Elastin Antikörper (Klon ELN-1981) (ABIN7878163) detektiert spezifisch Elastin in ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Elastin Antikörper (full length) (ABIN7878163)

Target: Elastin (ELN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Elastin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ELN-1981

Produktdetails anti-Elastin Antikörper

Bindungsspezifität: full length

Verwendungszweck: Elastin Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant full length human protein was used as the immunogen for the Elastin antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Titering of the Elastin antibody may be required for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Elastin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Elastin

Target: Elastin (ELN)

Andere Bezeichnung: Elastin

Hintergrund: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization