ECD/SGT1 Antikörper (full length)

Produktnummer ABIN7878151

Der Maus Monoklonal anti-ECD/SGT1 Antikörper (Klon PCRP-ECD-1D10) (ABIN7878151) detektiert spezifisch ECD/SGT1 in IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ECD/SGT1 Antikörper (full length) (ABIN7878151)

Target: ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ECD/SGT1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-ECD-1D10

Produktdetails anti-ECD/SGT1 Antikörper

Bindungsspezifität: full length

Verwendungszweck: ECD Antibody / SGT1

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the ECD antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ECD antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ECD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ECD/SGT1

Target: ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

Andere Bezeichnung: ECD

Hintergrund: Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.

UniProt: O95905

Pathways: Regulation of Carbohydrate Metabolic Process