ECD/SGT1 Antikörper (full length)
Kurzübersicht für ECD/SGT1 Antikörper (full length) (ABIN7878150)
Target
Alle ECD/SGT1 (ECD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- ECD Antibody / SGT1 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant full-length human protein was used as the immunogen for the ECD antibody.
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Isotyp
- IgG2b
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anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibody
ECD Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1A11 unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibodyECD Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-300) antibodyECD Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (C-Term) antibodyECD Reaktivität: Human, Ziege, Pferd, Rind (Kuh), Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 72-121) antibodyECD Reaktivität: Human, Ziege, Pferd, Kaninchen, Rind (Kuh), Schwein, Hund, Meerschweinchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 50-632) antibodyECD Reaktivität: Human, Maus, Ratte WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal dilution of the ECD antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the ECD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
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Andere Bezeichnung
- ECD
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Hintergrund
- Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
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UniProt
- O95905
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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