Desmin Antikörper (full length)
Kurzübersicht für Desmin Antikörper (full length) (ABIN7878128)
Target
Alle Desmin (DES) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
-
-
Bindungsspezifität
- full length
-
Verwendungszweck
- Desmin Antibody (azide and preservative free)
-
Aufreinigung
- Protein A/G affinity
-
Immunogen
- Recombinant full-length human desmin protein was used as the immunogen for the Desmin antibody.
-
Isotyp
- IgG1, kappa
-
-
-
-
Applikationshinweise
- Optimal dilution of the Desmin antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Konservierungsmittel
- Azide free
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the Desmin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- Desmin (DES)
-
Andere Bezeichnung
- Desmin
-
Hintergrund
- Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
-
UniProt
- P17661
Target
-