Rekombinanter CD81 Antikörper (full length)

Produktnummer ABIN7877953

Der Maus Monoklonal anti-CD81 Antikörper (Klon rC81-3442) (ABIN7877953) detektiert spezifisch CD81 in FACS, WB, IF, Func und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CD81 Antikörper (full length) (ABIN7877953)

Target: CD81

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RC81-3442

Produktdetails anti-CD81 Antikörper

Bindungsspezifität: full length

Verwendungszweck: Recombinant CD81 Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant full-length human CD81 protein was used as the immunogen for the recombinant CD81 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant CD81 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant CD811 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund: Recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C