Rekombinanter CD151 Antikörper (full length)

Produktnummer ABIN7877842

Der Kaninchen Monoklonal anti-CD151 Antikörper (Klon CD151-9297R) (ABIN7877842) detektiert spezifisch CD151 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter CD151 Antikörper (full length) (ABIN7877842)

Target: CD151

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD151 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: CD151-9297R

Produktdetails anti-CD151 Antikörper

Bindungsspezifität: full length

Verwendungszweck: Recombinant CD151 Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human CD151 protein was used as the immunogen for the recombinant CD151 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant CD151 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant CD151 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CD151

Target: CD151

Andere Bezeichnung: CD151

Hintergrund: CD151 is involved in a wide variety of cell biological processes, including cell adhesion and the transport of integrins via vesicles. The human CD151 gene maps to chromosome 11p15.5 and encodes a 253 amino acid protein, which belongs to the tetraspan (4TM) superfamily. CD151 can associate with several integrin chains including beta1, beta3, beta4, alpha2, alpha3, alpha5 and alpha6 integrins. CD151 may provide a framework for the spatial organization of both type I and type II hemidesmosomes, which are specialized junctional complexes that function as cell attachment sites for binding to basement membranes. CD151 RNA transcript (1.6 kb) can be detected in MO7e cells, bone marrow stromal cells, C11 endothelial cells, HUVEC and several myeloid leukemia cell lines, however, no transcript is detected in brain and the lymphoblastoid cell lines MOLT-4 and BALM-1. Leu 149-Glu 213 of CD151 is the interface through which Integrin alpha3/beta1 can bind. CD151 can enhance cell motility, invasion and metastasis of cancer cells in a focal adhesion kinase dependent manner.

UniProt: P48509