CREB5 Antikörper (full length)

Produktnummer ABIN7877764

Der Maus Monoklonal anti-CREB5 Antikörper (Klon PCRP-CREB5-1G8) (ABIN7877764) detektiert spezifisch CREB5 in WB, IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CREB5 Antikörper (full length) (ABIN7877764)

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CREB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-CREB5-1G8

Produktdetails anti-CREB5 Antikörper

Bindungsspezifität: full length

Verwendungszweck: CREB5 Antibody / CRE-BPa

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human CREB5 protein was used as the immunogen for the CREB5 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CREB5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CREB5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CREB5

Target: CREB5 (CAMP Responsive Element Binding Protein 5 (CREB5))

Andere Bezeichnung: CREB5

Hintergrund: The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.

UniProt: Q02930

Pathways: Thyroid Hormone Synthesis