CTBP2 Antikörper (full length)
Kurzübersicht für CTBP2 Antikörper (full length) (ABIN7877731)
Target
Alle CTBP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- full length
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Verwendungszweck
- CTBP2 Antibody / C-terminal-binding protein 2 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant full-length human CTBP2 protein was used as the immunogen for the CTBP2 antibody.
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal dilution of the CTBP2 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CTBP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
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Andere Bezeichnung
- CTBP2
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Hintergrund
- The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.
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UniProt
- P56545
Target
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