Rekombinanter Annexin a1 Antikörper (full length)

Produktnummer ABIN7877680

Der Maus Monoklonal anti-Annexin a1 Antikörper (Klon rANXA1-9145) (ABIN7877680) detektiert spezifisch Annexin a1 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Annexin a1 Antikörper (full length) (ABIN7877680)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RANXA1-9145

Produktdetails anti-Annexin a1 Antikörper

Bindungsspezifität: full length

Verwendungszweck: ANXA1 Antibody / Annexin A1

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human Annexin A1 protein was used as the immunogen for the ANXA1 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ANXA1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ANXA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: ANXA1

Hintergrund: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

UniProt: P04083

Pathways: Hormone Transport