IL-10RA Antikörper (Extracellular)

Produktnummer ABIN7877550

Der Ratte Monoklonal anti-IL-10RA Antikörper wird verwendet zum Nachweis von IL-10RA in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für IL-10RA Antikörper (Extracellular) (ABIN7877550)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-10RA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 1B1-3a

Produktdetails anti-IL-10RA Antikörper

Bindungsspezifität: Extracellular

Verwendungszweck: IL-10RA Antibody / IL-10R1

Aufreinigung: Protein G affinity chromatography

Immunogen: Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IL-10RA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Andere Bezeichnung: IL-10RA

Hintergrund: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

UniProt: Q61727

Pathways: Growth Factor Binding