IL-10RA Antikörper (Extracellular)
Kurzübersicht für IL-10RA Antikörper (Extracellular) (ABIN7877549)
Target
Alle IL-10RA (IL10RA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- Extracellular
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Verwendungszweck
- IL-10RA Antibody / IL-10R1 (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the IL-10RA antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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Andere Bezeichnung
- IL-10RA
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Hintergrund
- This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
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UniProt
- Q61727
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Pathways
- Growth Factor Binding
Target
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