Der Maus Monoklonal anti-Trefoil Factor 2 Antikörper (Klon GE16C) (ABIN7877488) detektiert spezifisch Trefoil Factor 2 in ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
TFF2 Antibody / Trefoil factor 2 (azide and preservative free)
Aufreinigung
PEG precipitation
Immunogen
A synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2 protein was used as the immunogen for this TFF2 antibody.
TFF2
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal dilution of the TFF2 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the TFF2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
Trefoil Factor 2 (TFF2)
Andere Bezeichnung
TFF2
Hintergrund
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.