Rekombinanter S100P Antikörper (C-Term)

Produktnummer ABIN7877474

Dieser Maus Monoklonal Antikörper detektiert spezifisch S100P in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter S100P Antikörper (C-Term) (ABIN7877474)

Target: S100P (S100 Calcium Binding Protein P (S100P))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100P Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RS100P-9254

Produktdetails anti-S100P Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Recombinant S100P Antibody / MIG9

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment corresponding to the C-terminus of human S100P/MIG9 protein was used as the immunogen for the recombinant S100P antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant S100P antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant S100P antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu S100P

Target: S100P (S100 Calcium Binding Protein P (S100P))

Andere Bezeichnung: S100P

Hintergrund: S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D. S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.

UniProt: P25815

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteine