Acetyl-CoA Carboxylase beta Antikörper (C-Term)

Produktnummer ABIN7877306

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Acetyl-CoA Carboxylase beta in WB, IHC (p) und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Acetyl-CoA Carboxylase beta Antikörper (C-Term) (ABIN7877306)

Target: Acetyl-CoA Carboxylase beta (ACACB)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-Acetyl-CoA Carboxylase beta Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ACACB Antibody / Acetyl-CoA carboxylase 2

Aufreinigung: Antigen affinity

Immunogen: A peptide from the C-terminal region of human Acetyl-CoA carboxylase 2 protein was used as the immunogen for this ACACB antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ACACB antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ACACB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Acetyl-CoA Carboxylase beta

Target: Acetyl-CoA Carboxylase beta (ACACB)

Andere Bezeichnung: ACACB

Hintergrund: Acetyl-CoA carboxylase 2 also known as ACC-beta or ACC2 is an enzyme that in humans is encoded by the ACACB gene. It is mapped to 12q24.11. Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

UniProt: O00763

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process