ITGA3 Antikörper (AA 96-324)

Produktnummer ABIN7877250

Der Kaninchen Polyklonal anti-ITGA3 Antikörper wird verwendet zum Nachweis von ITGA3 in Proben von Human. Er wurde validiert für WB, ELISA, FACS, IF und IHC (p).

Kurzübersicht für ITGA3 Antikörper (AA 96-324) (ABIN7877250)

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ITGA3 Antikörper

Bindungsspezifität: AA 96-324

Verwendungszweck: Integrin alpha 3 Antibody / ITGA3

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids L96-L324) was used as the immunogen for the Integrin alpha 3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Integrin alpha 3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ITGA3

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Andere Bezeichnung: Integrin alpha 3

Hintergrund: ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. This gene is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the ?3?1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex