Claudin 1 Antikörper (AA 96-211)

Produktnummer ABIN7877243

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Claudin 1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Claudin 1 Antikörper (AA 96-211) (ABIN7877243)

Target: Claudin 1 (CLDN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Claudin 1 Antikörper

Bindungsspezifität: AA 96-211

Verwendungszweck: CLDN1 Antibody / Claudin 1

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids F96-V211) was used as the immunogen for the CLDN1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CLDN1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CLDN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: CLDN1

Hintergrund: Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C