Der Kaninchen Polyklonal anti-RNF4 Antikörper (ABIN7877212) detektiert spezifisch RNF4 in WB, IHC (p) und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
The stated application concentrations are suggested starting points. Titration of the RNF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Aliquot the RNF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
RNF4
(Ring Finger Protein 4 (RNF4))
Andere Bezeichnung
RNF4
Hintergrund
The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.