PAICS Antikörper (AA 95-123)

Produktnummer ABIN7877211

Der Kaninchen Polyklonal anti-PAICS Antikörper wird verwendet zum Nachweis von PAICS in Proben von Human und Maus. Er wurde validiert für WB, FACS und IHC (p).

Kurzübersicht für PAICS Antikörper (AA 95-123) (ABIN7877211)

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAICS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PAICS Antikörper

Bindungsspezifität: AA 95-123

Verwendungszweck: ADE2 Antibody / PAICS

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 95-123 from the human protein was used as the immunogen for the ADE2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the ADE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ADE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PAICS

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Andere Bezeichnung: ADE2

Hintergrund: The PAICS gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P22234

Pathways: Chromatin Binding