Thrombomodulin Antikörper (AA 92-126)
Kurzübersicht für Thrombomodulin Antikörper (AA 92-126) (ABIN7877152)
Target
Alle Thrombomodulin (THBD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 92-126
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Verwendungszweck
- Thrombomodulin Antibody (N-Terminal Region)
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 92-126 from human THBD was used as the immunogen for the Thrombomodulin antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the Thrombomodulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Thrombomodulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Thrombomodulin (THBD)
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Andere Bezeichnung
- Thrombomodulin
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Hintergrund
- Thrombomodulin/THBD/TM/CD141 is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]
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UniProt
- P07204
Target
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