EIF4G2 Antikörper (AA 91-790)

Produktnummer ABIN7877147

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch EIF4G2 in WB, ELISA, IF, IP und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Affe.

Kurzübersicht für EIF4G2 Antikörper (AA 91-790) (ABIN7877147)

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4G2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-EIF4G2 Antikörper

Bindungsspezifität: AA 91-790

Verwendungszweck: DAP5 Antibody / EIF4G2 / Death-associated protein 5

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E91-E790) was used as the immunogen for the DAP5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the DAP5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the DAP5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu EIF4G2

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Andere Bezeichnung: DAP5

Hintergrund: Eukaryotic translation initiation factor 4 gamma 2, also called DAP-5 (Death-associated protein 5) and p97, is a protein that in humans is encoded by the EIF4G2 gene. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

UniProt: P78344