IDH3A Antikörper (AA 9-366)

Produktnummer ABIN7877079

Der Kaninchen Polyklonal anti-IDH3A Antikörper wird verwendet zum Nachweis von IDH3A in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IF, IHC (p) und FACS.

Kurzübersicht für IDH3A Antikörper (AA 9-366) (ABIN7877079)

Target: IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDH3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-IDH3A Antikörper

Bindungsspezifität: AA 9-366

Verwendungszweck: IDH3A Antibody / Isocitrate dehydrogenase [NAD] subunit alpha

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids K9-D366) was used as the immunogen for the IDH3A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IDH3A antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the IDH3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu IDH3A

Target: IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Andere Bezeichnung: IDH3A

Hintergrund: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3?) is an enzyme that in humans is encoded by the IDH3A gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

UniProt: P50213