SOGA2 Antikörper (AA 884-1522)

Produktnummer ABIN7877038

Der Kaninchen Polyklonal anti-SOGA2 Antikörper (ABIN7877038) detektiert spezifisch SOGA2 in WB, ELISA, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SOGA2 Antikörper (AA 884-1522) (ABIN7877038)

Target: SOGA2 (SOGA Family Member 2 (SOGA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOGA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-SOGA2 Antikörper

Bindungsspezifität: AA 884-1522

Verwendungszweck: MTCL1 Antibody / Microtubule cross-linking factor 1 / KIAA0802

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (K884-D1522) was used as the immunogen for the MTCL1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MTCL1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MTCL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SOGA2

Target: SOGA2 (SOGA Family Member 2 (SOGA2))

Andere Bezeichnung: MTCL1

Hintergrund: MTCL1 (microtubule cross-linking factor 1), also known as CCDC165 (Coiledcoil domain-containing protein 165), SOGA2 or MTCL1, is a 1,905 amino acid protein that localizes to the cell membrane, cytoplasm and cytoskeleton. MTCL1 is a microtubule-associated factor that plays a role in regulating polarization and microtubule dynamics as well as the development and maintenance of non-centrosomal microtubule bundles. MTCL1 is encoded by a gene that maps to chromosome 18 and is expressed as four isoforms due to alternative splicing events. Chromosome 18 encodes over 300 genes and contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF? modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.

UniProt: Q9Y4B5