PC Antikörper (AA 88-1165)

Produktnummer ABIN7877025

Der Kaninchen Polyklonal anti-PC Antikörper wird verwendet zum Nachweis von PC in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF, IHC (p) und FACS.

Kurzübersicht für PC Antikörper (AA 88-1165) (ABIN7877025)

Target: PC (Pyruvate Carboxylase (PC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-PC Antikörper

Bindungsspezifität: AA 88-1165

Verwendungszweck: Pyruvate Carboxylase Antibody / PC

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids R88-D1165) was used as the immunogen for the Pyruvate Carboxylase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Pyruvate Carboxylase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Pyruvate Carboxylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PC

Target: PC (Pyruvate Carboxylase (PC))

Andere Bezeichnung: Pyruvate Carboxylase

Hintergrund: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

UniProt: P11498