PFN2 Antikörper (AA 87-139)

Produktnummer ABIN7877014

Der Kaninchen Polyklonal anti-PFN2 Antikörper (ABIN7877014) detektiert spezifisch PFN2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Zebrafisch (Danio rerio).

Kurzübersicht für PFN2 Antikörper (AA 87-139) (ABIN7877014)

Target: PFN2 (Profilin 2 (PFN2))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PFN2 Antikörper

Bindungsspezifität: AA 87-139

Verwendungszweck: Zebrafish Pfn2 Antibody / Profilin 2 / Isoforms a & b

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Pfn2a/b recombinant protein (amino acids I87-F139) was used as the immunogen for the Zebrafish Pfn2 antibody. This antibody will detect the a and b isoforms.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Pfn2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Pfn2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PFN2

Target: PFN2 (Profilin 2 (PFN2))

Andere Bezeichnung: Pfn2

Hintergrund: Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

UniProt: Q6AZA1

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis