GCKR Antikörper (AA 8-569)

Produktnummer ABIN7876839

Der Kaninchen Polyklonal anti-GCKR Antikörper wird verwendet zum Nachweis von GCKR in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für GCKR Antikörper (AA 8-569) (ABIN7876839)

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCKR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GCKR Antikörper

Bindungsspezifität: AA 8-569

Verwendungszweck: Glucokinase Regulator Antibody / GCKR

Aufreinigung: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids Q8-Q569) was used as the immunogen for the Glucokinase Regulator antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Glucokinase Regulator antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Glucokinase Regulator antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Andere Bezeichnung: Glucokinase Regulator

Hintergrund: The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells). This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus