FLCN Antikörper (AA 8-551)

Produktnummer ABIN7876838

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FLCN in WB, ELISA, IF, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für FLCN Antikörper (AA 8-551) (ABIN7876838)

Target: FLCN (Folliculin (FLCN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FLCN Antikörper

Bindungsspezifität: AA 8-551

Verwendungszweck: Folliculin Antibody / FLCN

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids C8-K551) was used as the immunogen for the Folliculin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Folliculin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Folliculin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu FLCN

Target: FLCN (Folliculin (FLCN))

Andere Bezeichnung: Folliculin

Substanzklasse: Amino Acid

Hintergrund: Folliculin also known as FLCN, Birt-Hogg-Dube syndrome protein or FLCN_HUMAN is a protein that in humans is associated with Birt-Hogg-Dube syndrome and hereditary spontaneous pneumothorax. It is encoded by the Folliculin (FLCN) gene (alias BHD, FLCL) that acts as a tumor suppressor gene. It is mapped to 17p11.2. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization