SNX15 Antikörper (AA 8-327)

Produktnummer ABIN7876821

Der Kaninchen Polyklonal anti-SNX15 Antikörper wird verwendet zum Nachweis von SNX15 in Proben von Human. Er wurde validiert für ELISA und WB.

Kurzübersicht für SNX15 Antikörper (AA 8-327) (ABIN7876821)

Target: SNX15 (Sorting Nexin 15 (SNX15))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX15 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-SNX15 Antikörper

Bindungsspezifität: AA 8-327

Verwendungszweck: Sorting nexin 15 Antibody / SNX15

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids D8-K327) was used as the immunogen for the Sorting nexin 15 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Sorting nexin 15 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Sorting nexin 15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Andere Bezeichnung: Sorting nexin 15

Hintergrund: Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

UniProt: Q9NRS6