SYCP3 Antikörper (AA 75-236)

Produktnummer ABIN7876729

Der Kaninchen Polyklonal anti-SYCP3 Antikörper (ABIN7876729) detektiert spezifisch SYCP3 in WB, ELISA, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SYCP3 Antikörper (AA 75-236) (ABIN7876729)

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYCP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-SYCP3 Antikörper

Bindungsspezifität: AA 75-236

Verwendungszweck: Synaptonemal Complex Protein 3 Antibody / SYCP3

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E75-F236) was used as the immunogen for the Synaptonemal Complex Protein 3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Synaptonemal Complex Protein 3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Synaptonemal Complex Protein 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SYCP3

Target: SYCP3 (Synaptonemal Complex Protein 3 (SYCP3))

Andere Bezeichnung: Synaptonemal Complex Protein 3

Hintergrund: SYCP3, also known as COR1 or SCP3, is a protein that in humans is encoded by the SYCP3 gene. It is mapped to 12q23.2. This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. SYCP3 has an essential meiotic function in human spermatogenesis that is compromised by the mutant protein by dominant-negative interference. SYCP3 is linked to inherited aneuploidy in female germ cells and provides a model system for studying age-dependent degeneration in oocytes.

UniProt: Q8IZU3