GLN1 Antikörper (AA 74-371)

Produktnummer ABIN7876716

Der Kaninchen Polyklonal anti-GLN1 Antikörper wird verwendet zum Nachweis von GLN1 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC (p).

Kurzübersicht für GLN1 Antikörper (AA 74-371) (ABIN7876716)

Target: GLN1 (Glutamine Synthetase (GLN1))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GLN1 Antikörper

Bindungsspezifität: AA 74-371

Verwendungszweck: Zebrafish Glutamine synthetase Antibody / Glula / Glulb

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Glula/b recombinant protein (amino acids N74-Y371) was used as the immunogen for the Zebrafish Glutamine synthetase antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Glutamine synthetase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Glutamine synthetase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GLN1

Target: GLN1 (Glutamine Synthetase (GLN1))

Andere Bezeichnung: Glutamine synthetase

Hintergrund: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

UniProt: Q7T2P7

Pathways: Positive Regulation of Peptide Hormone Secretion