CD207 Antikörper (AA 74-213)

Produktnummer ABIN7876709

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD207 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD207 Antikörper (AA 74-213) (ABIN7876709)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: LGRN-1821

Produktdetails anti-CD207 Antikörper

Bindungsspezifität: AA 74-213

Verwendungszweck: Langerin Antibody / CD207

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 74-213) was used as the immunogen for the Langerin antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Langerin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Langerin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: Langerin

Hintergrund: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

UniProt: Q9UJ71