Rekombinanter CD207 Antikörper (AA 74-213)
Kurzübersicht für Rekombinanter CD207 Antikörper (AA 74-213) (ABIN7876704)
Target
Alle CD207 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 74-213
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Verwendungszweck
- Recombinant Langerin Antibody / CD207 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A portion of amino acids 74-213 was used as the immunogen for the recombinant Langerin antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the recombinant Langerin antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the recombinant Langerin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD207 (CD207 Molecule, Langerin (CD207))
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Andere Bezeichnung
- Langerin
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Hintergrund
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
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UniProt
- Q9UJ71
Target
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